Sister's Keeper is an action-drama about a military-trained assassin, Jacob Tate (Kent Faulcon), who has been sent by his handler (Eric Roberts) to eliminate a beautiful, small-town, school teacher, Diane Shaw (Denise Boutte).  When Diane mistakes Jacob for her long-lost brother, he uses the guise to find the perfect moment to kill her, but soon finds himself drawn into her frank and colorful, Southern family.  The professional killer is left to choose between doing what he knows - murder for money - and doing what he knows is right - finding out who wants the innocent Diane dead.